甲状腺 機能 低下: 診断 と 治療
Anne Mounsey1, Ryan Paulus1, Wesley Roten1
1University of North Carolina, Chapel Hill.
American family physician
|August 20, 2025
まとめ
甲状腺ホルモンの過剰生産である甲状腺症は,米国の成人の1.3%に影響します. 診断は低チロトロピンレベルに依存し,最も一般的な原因はグレイヴス病です.
科学分野:
- 内分泌学
- 内科 医学
背景:
- 甲状腺機能不全は 甲状腺ホルモンの過剰産生で アメリカの成人の1.3%に 影響を及ぼします
- 甲状腺ホルモンが過剰な状態である甲状腺毒性症は 甲状腺炎,甲状腺炎,または外因的な原因から生じる可能性があります.
- 一般的な症状には,弱気,心拍,体重減少,熱不耐性があります. 症状には,,心拍,筋肉の弱気,震えがあります.
研究 の 目的:
- 甲状腺機能過剰症の原因,診断,治療について概要を述べる.
- 甲状腺毒性の様々な原因を区別する.
- 甲状腺機能過剰症の治療方法を検討する.
主な方法:
- 低甲状腺刺激ホルモン (チロトロピン) が診断基準です.
- 最も一般的な原因であるグラブス病は,甲状腺眼疾患またはチロトロピン受容体抗体によって特定されます.
- 放射性ヨウ素のスキャンでは 毒性多胞性や 甲状腺炎などの原因が区別されます
主要な成果:
- ティオナミド (例えばメチマゾール) はグレイブス病の寛解を誘発し,他の形態を制御する.
- 放射性ヨウ素は,グレイブズ病と多胞性の症例の90%以上を効果的に治療します.
- 低甲状腺症は放射性ヨウ素治療の1年後の一般的な結果です.
結論:
- 甲状腺機能過剰症の治療は,病因と患者の症状によって異なります.
- ティオナミド,放射性ヨウ素,甲状腺切除が主な治療方法である.
- 甲状腺切除は,圧縮症状を引き起こすで好ましい.
関連する概念動画
Synthesis and Regulation of Thyroid Hormones
5.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
5.1K
Diabetes: Management and Pharmacotherapy
362
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
362
The Thyroid Gland
4.3K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.3K
Increased pulse rate
748
Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
748
Functions of Thyroid Hormones
3.2K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
3.2K
Chronic Kidney Disease III: Interprofessional Care
78
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
78


