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Updated: Sep 10, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
11:45

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

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アザスガー基のスルフォナミドに関する研究:新種の炭酸アンヒドラゼ阻害剤

Debora Pratesi1, Francesco Brenzini Biagioni1, Camilla Matassini1

  • 1Dipartimento di Chimica 'Ugo Schiff', Università degli Studi di Firenze, via della Lastruccia 3-13, Sesto Fiorentino, FI 50019, Italy.

Bioorganic chemistry
|August 20, 2025
PubMed
まとめ

研究者らはヒト炭酸水素酵素 (hCA) 阻害のための新しいアザシュガー誘導体を調査し,トリアゾールリングの除去が腫瘍に関連したhCA IXおよび他の臨床的に重要な同型体の阻害を強めたことを発見しました.

キーワード:
ベンゼンスルフォナミド炭酸アンヒドラスグリコミメティック選択的抑制チオウリアトリアゾール尿素

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Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid05:08

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