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Updated: Sep 10, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
11:32

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

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YBX1を標的とする: 細胞老化とmTORシグナル伝達の制御による胃がんに対する新しい治療戦略

Wenze Zhang1, Yanjuan Jia2, Anqi Wang2

  • 1The First College of Clinical Medicine, Lanzhou University, Lanzhou 730000, China; NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor, Gansu Provincial Hospital, Lanzhou 730000, China.

Tissue & cell
|August 20, 2025
PubMed
まとめ

Yボックス結合タンパク質1 (YBX1) は胃がん (GC) の成長を促進し,老化を阻害する. YBX1をターゲットにすることで,GC治療の改善のために,衰老を誘発し,癌細胞の死滅を強化することで,新しい"ワン・トゥー・パンチ"療法が提供されます.

キーワード:
細胞の老化胃がんROS について標的型療法YBX1 についてmTORシグナリング

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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT10:28

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Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs10:32

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

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