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Updated: Sep 10, 2025

Measuring Relative Insulin Secretion using a Co-Secreted Luciferase Surrogate
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Measuring Relative Insulin Secretion using a Co-Secreted Luciferase Surrogate

Published on: June 25, 2019

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GLP-1媒介のインスリン分泌を増強する

Abigail Pearce1, Poonam Kumari2, Claudia M Sisk1

  • 1Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK.

The Journal of biological chemistry
|August 20, 2025
PubMed
まとめ

レセプター活性調節タンパク質3 (RAMP3) は,グルカゴン様ペプチド-1受容体 (GLP-1R) のシグナル伝達を調節し,インスリン分泌を増強する. この相互作用は,糖尿病と肥満の現在のGLP- 1R療法に関連した副作用を軽減する可能性があります.

キーワード:
アロステル規制カルシウムの細胞内放出糖尿病G タンパク質結合受容体第二の使者インスリン分泌

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