症状のあるアピカル・歯周病で,以前治療を受けた歯の根管にカルシウム水酸化物を置いた後のエンドトキシンレベル: ランダム化制御臨床試験
Dhvani Sunil Pandya1, Selvakumar Kritika1, Kavitha Sanjeev1
1Department of Conservative Dentistry and Endodontics, SRM Dental College, SRM Institute of Science &Technology, Ramapuram Campus, Chennai, Tamil Nadu, India.
Journal of endodontics
|August 20, 2025
まとめ
継続的なケラート灌は,アピカル歯周炎の歯でカルシウム水酸化物による連続ケラートよりも効果的にエンドトキシンを減少させました.
科学分野:
- エンドドンティクス
- 微生物学
- 生物化学
背景:
- グラム陰性細菌の炎症性成分であるエンドトキシンが,アピカル歯周炎に関与している.
- 根管治療の成功には 効果的な内毒素の減少が不可欠です
研究 の 目的:
- エンドトキシン減少における連続ケラ化 (CC) 灌と連続ケラ化 (SC) を比較する.
- エンドトキシン減少のためにSCの後にカルシウム水酸化物 (CH) の配置の追加の利益を評価する.
主な方法:
- 症状のあるアピカル歯周炎の48本の歯を対象としたランダム化臨床試験.
- 根管のサンプルを採取した.
- エンドトキシン濃度は,リムルス・アメボシート・リサート・アッセイを用いて定量化されました.
主要な成果:
- CCとSCの両方が化学的調製後に内毒素を著しく減少させた.
- CC灌は,すべての処理後の時点において,SCよりもendotoxin濃度が著しく低いことを示した.
- CH置換に続く配列ケレーションは,さらに内毒素の減少を示したが,CCよりも高いままでした.
結論:
- カルシウム水酸化物による連続ケラチウム灌は,ケラチウム水酸化物による連続ケラチウム灌と比較して,エンドトキシンを減少させるのにより効果的です.
- この発見は,アピカル歯周炎の根管消毒プロトコルの最適化に関する新しい洞察を提供します.
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