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Updated: Sep 10, 2025

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
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癌による神経損傷は,抗PD-1 治療に対する耐性を促進する

Erez N Baruch1,2, Frederico O Gleber-Netto3, Priyadharsini Nagarajan4

  • 1Division of Cancer Medicine, Hematology and Oncology Fellowship program, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Nature
|August 20, 2025
PubMed
まとめ

周神経侵入 (PNI) とがんによる神経損傷 (CINI) は,抗PD-1 治療への反応を阻害する. IL-6の無神経化や阻害のようなCINI経路をターゲットにすることで,様々ながんの治療効果が回復できます.

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