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Updated: Sep 10, 2025

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ダイノルフィンAは,SP-1を増加させることで,骨髄腫細胞のミトコンドリア生殖を阻害する

Yaxiong Dai1, Jian Zhang2, Yingzhen Peng3

  • 1Department of Orthopedics, Huanggang Central Hospital of Yangtze University, Huanggang, China.

Journal of biochemical and molecular toxicology
|August 21, 2025
PubMed
まとめ

ダイノルフィンAは,ミトコンドリア機能とバイオゲネシスを妨害することで,骨肉腫細胞の生存能力を低下させます. このペプチド誘発の細胞毒性は,エネルギー生産の低下とミトコンドリアの成長の抑制を含み,骨髄腫 (OS) の潜在的な治療戦略を提供します.

キーワード:
ダイノルフィンAPGC-1αについてSP-1 についてミトコンドリアの生体生成オステオサルコマ

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