関連する実験動画

Updated: Sep 10, 2025

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
11:42

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

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miRNA が肝臓細胞がんにおける表皮細胞-メゼンキマ移行の異なる Nrf1 と Nrf2 の調節を媒介する対立するメカニズム

Juan Chen1,2, Jing Feng1, Yuping Zhu1,3

  • 1The Laboratory of Cell Biochemistry and Topogenetic Regulation, College of Bioengineering & Faculty of Medical Sciences, Chongqing University, Chongqing, China.

RNA biology
|August 21, 2025
PubMed
まとめ

核因子エリソイド2関連因子1 (Nrf1) は,miR-3187-3pを活性化することによって,肝細胞癌 (HCC) の転移を予防し,Nrf2はmiR-1247-5pを活性化することによって,転移を促進する. これは,上皮質-メゼンキマ移行 (EMT) の調節における異なる役割を明らかにする.

キーワード:
CDH1 についてCDH2 についてEMT についてMMP15 についてMMP17 についてNrf1 についてNrf2 についてSNAI1 について肝がんの転移マイクロRNA (miRNA)

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