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Updated: Sep 10, 2025

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
13:08

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Published on: September 9, 2012

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リコンビナント活性化因子VIIの低濃度は,アベラシマブin vitroによって誘発された粘性弾性試験パラメータの変化を逆転させることで,凝固パターンを正常化する

Yasser Khder1, Serge Côté2, Klaus Peter Hoffmann3

  • 1Anthos Therapeutics, Cambridge, Massachusetts, USA.

Research and practice in thrombosis and haemostasis
|August 21, 2025
PubMed
まとめ

リコンビネント活性化因子VIIa (rFVIIa) の低用量は,FXI/ FXIa阻害剤であるアベラシマブの抗凝固効果を効果的に逆転させた. これは,rFVIIaがアベラシマブで治療された患者の出血を制御することを示唆しています.

キーワード:
ロテムアベラシマブ抗凝固剤XIa因子阻害剤リコンビネントFVIIa

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