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Updated: Sep 10, 2025

Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
08:15

Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease

Published on: May 10, 2024

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ファーネソイドX受容体の活性化により,免疫グロブリン結合タンパク質の発現が上昇し,糖尿病性腎臓病が緩和される

Jian-Ying Tang1, Yuan-Jia Chong1, Lu Yang1

  • 1Department of Nephrology, University-Town Hospital of Chongqing Medical University, Chongqing 401331, China.

World journal of diabetes
|August 21, 2025
PubMed
まとめ

ファルネソイドX受容体 (FXR) の活性化により,免疫グロブリン結合タンパク質 (BiP) の発現が促進され,エンドプラズマ網膜ストレス (ERS) 経路が抑制されます. この研究は,FXRを糖尿病性腎不全 (DN) の潜在的な治療標的として特定しています.

キーワード:
結合免疫グロブリンタンパク質クロマチン 免疫 降水糖尿病性腎臓病エンドプラズマの網膜のストレスファルネソイドX受容体

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