悪性阻害に対する皮膚経由で置かれた金属胆道ステントの合併症: 系統的レビュー
Jonathan Bock1, Christopher J Reisenauer2, Michael C Jundt2
1Mayo Clinic Alix School of Medicine, Mayo Clinic, Rochester, MN, United States.
Frontiers in radiology
|August 21, 2025
まとめ
悪性胆道阻害に対する皮膚経由の金属胆道ステントの設置は高い成功率を示しています. 患者の約19%が合併症を経験したが,大半は軽微で,安全性プロファイルが好ましいことを示した.
科学分野:
- 介入放射線学
- 胃腸内科
- 腫瘍学
背景:
- 悪性胆道阻害は大きな課題です
- 皮膚を貫通する金属ステントは,緩和と治療のために使用されます.
研究 の 目的:
- 経皮メタリック胆管ステントの通透性と合併症を体系的に検討する.
- 悪性胆道阻害のアウトカムを評価する.
主な方法:
- PRISMAのガイドラインに従って体系的なレビューを行う.
- EMBASEとPubMedの文献検索 (スクリーニングした記事は891件,18件)
- ニューカッスル・オタワスケールによる品質評価;人口統計,成功,合併症に関するデータ抽出.
主要な成果:
- 1,453人の患者が含まれており,加重された技術的な成功率は97. 7%でした.
- ステントの閉塞は13. 5%で発生し,合併症は19. 1% (87重症) であった.
- 一般的な合併症: 炎 (6. 4%),胆炎 (4. 8%),出血 (4. 4%),手術による死亡 (0. 4%)
結論:
- 皮膚経由の金属ステントの設置は悪性胆道阻害に対する高い技術的成功を示しています.
- ステント閉塞の低率と管理可能な合併症のプロファイルが観察されました.
- ほとんどの合併症は軽微で 全体の安全性を裏付けました
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