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Updated: Sep 10, 2025

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data
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Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Published on: June 24, 2021

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ALDEx2によるRNAシーケンシングカウントデータの分析のための明示的なスケールシミュレーション

Gregory B Gloor1, Michelle Pistner Nixon2, Justin D Silverman3,4,5

  • 1Department of Biochemistry, University of Western Ontario, London ON, N6A 5C1, Canada.

NAR genomics and bioinformatics
|August 21, 2025
PubMed
まとめ

スケールモデルは,生物学的システムのサイズを考慮し,高通量シーケンシング (HTS) データのエラーを減らすことで,トランスクリプトミックの分析を改善します. これは,差異的多量分析の正確性と再現性を高めます.

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関連する概念動画

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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