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Updated: Sep 10, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay

Published on: February 9, 2021

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選択性エストロゲン受容体調節剤の公式合成,テトラヒドロフローレノン構造を用いて [3 + 2 + 1] 亜ビニルチクロプロパンとCOのサイクル添加

Jing Zhang1, Guanyu Zhang2, Hongxi Bai2

  • 1Pingshan Translational Medicine Center, Shenzhen Bay Laboratory, Shenzhen, 518118, China.

Beilstein journal of organic chemistry
|August 21, 2025
PubMed
まとめ

新しい11段階の合成により,テトラヒドロフルレノン構造の製品VIが作成されました. この化合物は選択的なエストロゲン受容体調節剤として作用し,潜在的な治療用途に不可欠です.

キーワード:
[3 + 2 + 1]サイクル添加選択的なエストロゲン受容体調節剤合成テトラヒドロフローレノン

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