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Updated: Sep 10, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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鉄単原子の酵素媒介による硫化水素の供給は,フェロプトーシスの感受性を誘導する反応性酸素種カスケードを増幅する

Xuegang Niu1,2,3, Penghui Wei1,2, Mingtao Zhu1,4

  • 1Department of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350005, China.

Materials today. Bio
|August 21, 2025
PubMed
まとめ

この研究は,がん細胞におけるフェロプトーシスを強化する新しい鉄単原子酵素ナノプラットフォーム (Fe/SAE@A) を導入しています. 脂質過酸化と癌細胞死を増幅するROSの除去を抑制する硫化水素 (H2S) を供給します.

キーワード:
触媒療法フェロプトーシス硫化水素反応性酸素種単原子酵素

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