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Updated: Sep 10, 2025

Single-cell RNA-Seq of Defined Subsets of Retinal Ganglion Cells
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対立グラフ対照学習を用いた単細胞RNA-seqの深層クラスタリング

Le Van Vinh1, Tran Nhat Quang2, Lai Hoang Hiep1

  • 1Faculty of Information Technology, HCMC University of Technology and Education, Vo Van Ngan Street, Ho Chi Minh City 700000, Vietnam.

Briefings in bioinformatics
|August 21, 2025
PubMed
まとめ

この研究では,単細胞RNAシーケンシング (scRNA-seq) データクラスタリングのための新しい方法であるscAGCLを導入します. scAGCLは対抗グラフ対照学習を使用して,細胞タイプ分類を改善し,既存のアルゴリズムを上回るマーカー遺伝子を識別します.

キーワード:
敵対的な攻撃クラスタリング対照的学習グラフニューラルネットワーク単細胞RNA-seq

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RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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