関連する実験動画

Updated: Sep 10, 2025

Identification of RNAs Engaged in Direct RNA-RNA Interaction with a Long Non-Coding RNA
07:24

Identification of RNAs Engaged in Direct RNA-RNA Interaction with a Long Non-Coding RNA

Published on: July 9, 2021

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LncPTPred: クロスリンクと免疫プレシピテーション (CLIP-Seq) のデータに基づく lncRNA-タンパク質の相互作用を予測する

Gourab Das1, Troyee Das1, Zhumur Ghosh1

  • 1Department of Biological Sciences, Bose Institute, Unified Academic Campus, Kolkata 700 091, West Bengal, India.

Briefings in bioinformatics
|August 21, 2025
PubMed
まとめ

機械学習ツールであるLncPTPredを開発し,ロングノンコーディングRNA (lncRNA) - タンパク質相互作用 (LPI) を予測しました. この計算によるアプローチは LPI の発見を加速し,既存の方法を上回り,実験的検証を導くことができます.

キーワード:
CLIP-Seq についてハイパーパラメータ最適化lncRNA タンパク質の相互作用機械学習

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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