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Updated: Sep 10, 2025

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
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ミトコンドリアタンパク質:HCCにおける悪性進行の潜在的な病理学的メカニズム

Yicun Liu1, Yawen Shao2, Xudong Zhu3

  • 1Department of Gastroenterology and Hepatology, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, Jiangsu, China.

PloS one
|August 21, 2025
PubMed
まとめ

ミトコンドリアのタンパク質は,肝細胞癌 (HCC) で差異的に発現し,腫瘍の進行に影響を与えます. FDPS,DNA2,MYO19のような特定のタンパク質は,変化した発現を示し,予後不良と相関し,HCCの潜在的な治療標的を提供します.

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