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Updated: Sep 10, 2025

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy
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Published on: January 31, 2025

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CAFによって分泌される脂肪酸は,脂質ラフト形成による口腔がんの進行を促す

Jingtian Mu1, Tingpei Ye1, Junjiang Liu1

  • 1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China.

Archives of oral biology
|August 21, 2025
PubMed
まとめ

癌に関連した線維細胞 (CAF) は自由脂肪酸 (FFA) を供給し,口腔がん細胞は脂質の浮遊体を形成し,がん促進信号を活性化し,悪性腫瘍を駆動します. このCAF-FFA-リピッド・ラフト・パスをターゲットにすることで 新しい治療法が生まれます

キーワード:
癌の進行癌に関連した線維芽細胞脂肪酸リピッド・ラフト口腔状細胞がん

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