シグモイド結腸の悪性周回神経腫:症例報告と公表された症例との比較
Mohammed Mohammed Al-Shehari1, Khaled Sultan Galeb2, Wael Abdu Ahmed3
1Department of Surgery, Faculty of Medicine and Health Science, Sana'a University, Sana'a City, Yemen; Department of Surgery, Al-Thawra Modern General Hospital, Sana'a City, Yemen.
悪性周回神経腫 (MPNST) は,まれな攻撃的な肉腫である. 大腸のMPNSTでは完全な切除が重要ですが,再発率は40%近くで,長期の追跡が必要になります.
科学分野:
- 腫瘍学
- 胃腸内科
- 外科病理学
背景:
- 周回神経の悪性腫瘍 (MPNSTs) は,希少で攻撃的な軟組織肉腫である.
- シグモイド結腸のMPNSTは極めてまれで,診断と治療に問題がある.
研究 の 目的:
- 結腸MPNSTの 珍しい症例を報告する
- 胃腸道におけるMPNSTの診断課題と治療戦略を強調する.
主な方法:
- レクトシグモイド腫の46歳の女性です
- 画像検査,大腸内視鏡検査,組織病理学,免疫ヒストケミストリーを含む診断検査.
- 手術で切除した
主要な成果:
- S-100とSOX-10陽性で確認されたMPNSTと診断された大きな多胞性潰瘍.
- 完全な切除手術が成功し,明確な限界が達成されました.
- 8件の文献レビューでは, ~40%の再発率を示した.
結論:
- 大腸のMPNSTは,希少性と非特異的な症状のために診断に困難があります.
- 免疫ヒストケミストリーは,MPNSTを他のメゼンキーマ腫瘍と区別するのに極めて重要です.
- 再発の可能性が高いため,完全な外科的切除と長期の追跡が不可欠です.
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