リウマティック疾患における胎児と母親の不良心的アウトカム: 系統的レビュー
E Manouchehri1, N Jazayerinezhad2, Z Oskoueyan3
1Assistant Professor of Reproductive Health, Department of Nursing and Midwifery, MMS.C., Islamic Azad University, Mashhad, Iran.
まとめ
妊娠中の自己免疫性リウマチ症 (ARD) の治療には,共同治療が必要です. これらの複雑な妊娠において,母親と胎児の心的結果を改善するために, 調整された管理戦略は極めて重要です.
科学分野:
- リウマトロジ
- 心臓病科
- 妊婦と胎児の医療
背景:
- 自己免疫性リウマチック疾患 (ARD) は,妊娠中に独特の課題を提示します.
- 合併症は,疾患の活動と治療によって大きく異なります.
研究 の 目的:
- ARDの妊婦における母体および胎児の心臓のアウトカムを体系的に検討する.
- 常見の有害な心血管疾患と危険因子を特定する.
主な方法:
- 2024年8月まで,電子データベースの包括的なシステマティック・レビューが行われました.
- 1500万人以上の女性を対象とした53件の研究が含まれています.
- ミックス・メソッド・アセスメント・ツール (MMAT) を使用してバイアスのリスクを評価した.
主要な成果:
- システミック・ルプス・エリテマトーサスとタカヤス関節炎は,最も頻繁に研究されたARDでした.
- 妊娠前出血症- 出血症は,最も一般的な母性心血管症状でした.
- 胎児/新生児の心臓発作の最も頻繁なアウトカムは先天性心臓閉塞でした.
- リウマチ関節炎の結果は論争の的であり,96%の研究ではバイアスのリスクがあった.
結論:
- ARDの妊婦の管理には 総合的な共同ケアが不可欠です
- 適切なケアが 母親と胎児の両方にとって 成果を上げます
- バイアスや議論の余地のある発見に対処するためにさらなる研究が必要である.
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