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SLE の 患者 の 孤独 と 鬱: ブラジル の サンプル の 中 で 行なわ れ た 横断 研究
Valentina Garofani Ramos1, Maria Eduarda Pelaez de Campos1, Thelma Skare1
1Mackenzie Evangelical School of Medicine, Curitiba, Brazil.
Journal of psychosomatic research
|August 21, 2025
まとめ
システム性白血球症 (SLE) 患者における孤独感のレベルは,対照群と類似しており,うつ病と相関しています. 孤独感は,SLE患者の病気の活動や損傷と関連づけられませんでした.
科学分野:
- リウマトロジ
- 心理学
- 公衆衛生
背景:
- システム性白血球症 (SLE) のような慢性疾患は 孤独感のリスクを高めます
- 孤独は慢性疾患の患者の臨床状態に悪影響を及ぼします.
研究 の 目的:
- SLE患者と対照群の孤独感を評価する.
- 孤独 と うつ病,病気 の 活動,SLE 患者 の 損傷 と の 関係 を 調べる.
主な方法:
- 109人のSLE患者と92人の対照群は,うつ病 (CES- D),孤独感 (UCLA- BR),疾患活動 (SLEDAI),および損傷 (SLICC/ ACR DI) について検証されたスケールを完了しました.
- 臨床的および疫学的変数も収集した.
主要な成果:
- SLE患者は対照群よりもうつ病の症状を多く報告しましたが,孤独感のスコアは同様でした.
- 孤独感はSLE患者と対照群の両方でうつ病と強く相関していました.
- 孤独感とSLE疾患の活動,累積的な損傷,または疾患の持続時間との間に有意な関連は見つかりませんでした.
- SLE 患者の孤独感の増大と,家族関係に対する悪質な認識が関連していた.
結論:
- 孤独感のレベルはSLE患者と対照群の間で比較できます
- 鬱病は2つのグループにおける 孤独感の重要な相関関係です
- SLE患者における孤独感は,疾患の活動,累積的な臓器損傷,または臨床的変数と関連していません.
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