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Updated: Sep 10, 2025

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
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重度のうつ病および統合失調症における脳脊髄液におけるシナプスタンパク質SNAP-25の減少に関する証拠

Petra Steinacker1, Leonie Werner2, Alexander Tarabuko1

  • 1Department of Neurology, Martin Luther University Halle Wittenberg, Halle (Saale), Germany.

BMJ mental health
|August 21, 2025
PubMed
まとめ

脳脊髄液中の25 kDaのシナプトソーマ関連タンパク質 (SNAP-25) レベルは,重度うつ病 (MDD) と統合失調症 (SCZ) の患者で低下し,診断に有用である可能性を示唆しています. このシナプスマーカーは,MDDにおけるシナプス機能の低下を示します.

キーワード:
横断的な研究うつ病

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