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Updated: Sep 10, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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palmoplantar pustulosisにおけるジャヌスキナーゼ阻害剤:混合法可行性試験 (JAKPPPOT) プロトコル

David Gleeson1, Sarah Chapman2, Helen McAteer3

  • 1St. John's Institute of Dermatology, Guy's & St. Thomas' NHS Foundation Trust and King's College London, London, UK.

BMJ open
|August 21, 2025
PubMed
まとめ

この研究は,パルモプランタール・プストゥロシス (PPP) の治療に,ウパダシチニブのようなジャヌスキナーゼ (JAK) 阻害剤の使用の可能性を評価するものです. この結果は,PPP患者におけるJAK阻害剤の有効性および安全性に関する将来のランダム化対照試験の指針となる.

キーワード:
大人の皮膚科臨床試験実現可能性研究牛皮病

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