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ITKの過剰発現は,TCR-Ca2+-Calcineurin-NFAT-IFN-γ経路を通じて,DLBCLに対するT細胞細胞毒性を高める

  • 0Department of Laboratory, Henan Provincial People's Hospital, Zhengzhou, 450003, China.
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2025年8月21日

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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