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Somatosensation

Somatosensation

The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.

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関連する実験動画

Updated: Sep 10, 2025

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

腕の切断前と後の安定した皮質の身体マップ

Hunter R Schone^1,2,3,4, Roni O Maimon-Mor^5,6,7, Mathew Kollamkulam^5,8

¹Institute of Cognitive Neuroscience, University College London, London, UK. schonehunter@gmail.com.

Nature neuroscience

|August 21, 2025

まとめ

大人の脳の可塑性は議論されている. この研究では腕の切断から5年後でさえも手と唇の脳の地図が安定しており大規模な皮質の再編成は起こらないことが示されています

さらに関連する動画

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

Controlled Cortical Impact Model of Mouse Brain Injury with Therapeutic Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Cells

Controlled Cortical Impact Model of Mouse Brain Injury with Therapeutic Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Cells

Published on: July 10, 2019

関連する実験動画

Last Updated: Sep 10, 2025

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

Controlled Cortical Impact Model of Mouse Brain Injury with Therapeutic Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Cells

Controlled Cortical Impact Model of Mouse Brain Injury with Therapeutic Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Cells

Published on: July 10, 2019

科学分野:

神経科学
神経イメージング
脳の可塑性

背景:

大人の脳が傷を負った後の再編成 (皮質の可塑性) を完全に理解していない.
以前の研究では肢体喪失後の脳の再編成の程度について矛盾する証拠が提示されています

研究の目的:

腕の切断後の大人の皮質の再編成を調査する
手と唇の動きの脳活動パターンを切断前と切断後の長期間に比べるため

主な方法:

長距離神経イメージング (fMRIまたは類似) が使用されました.
3人の成人は腕の切断前と5年後にスキャンされました
無傷の手/幻の手と唇の動きを測った.

主要な成果:

手と唇の両方の皮質表現は,主感覚運動領域で安定したままでした.
アクティビティの変化を直接定量化すると,有意な大規模な皮質の再編成は認められませんでした.
幻肢と唇の動きに関連した脳活動パターンは時間の経過とともに一貫していました

結論:

大人の脳は腕の切断のような大きな変化にもかかわらず皮質の表現において驚くべき安定性を発揮します
大規模な皮質の再編成は大人の腕切断の必然的な結果ではありません
感覚運動皮質のマップは解剖後長期にわたって回復力と安定性を示しています