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Updated: Sep 10, 2025

Analysis of Cell Cycle Position in Mammalian Cells
12:19

Analysis of Cell Cycle Position in Mammalian Cells

Published on: January 21, 2012

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BRCA1およびBRCA2遺伝子発現:p53-および細胞サイクル依存抑制にはRBとDREAMが必要です

Marianne Quaas1,2, Robin Kohler1, Lukas Nöltner1

  • 1Molecular Oncology, Faculty of Medicine, University of Leipzig, Leipzig, Germany.

Cell death and differentiation
|August 21, 2025
PubMed
まとめ

DNA修復に不可欠なBRCA1およびBRCA2遺伝子の発現は,細胞サイクル停止およびDNA損傷中にp53および抑制器複合体によって抑制されます. このシフトは誤りやすい修復を促進し,悪性変異を防ぐ.

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