Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Metastasis02:30

Metastasis

5.7K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.7K
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

906
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
906
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

3.1K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
3.1K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Targeting KRAS codon 13 mutations using direct combination approaches in non-small cell lung cancer.

Cancer discovery·2026
Same author

Selpercatinib in Early-Stage <i>RET</i> Fusion-Positive Non-Small-Cell Lung Cancer.

The New England journal of medicine·2026
Same author

Sex Impacts Progression-Free Survival of Alectinib through Drug Exposure in Patients with <i>ALK-</i>Positive Non-Small Cell Lung Cancer.

Cancer communications (London, England)·2026
Same author

Antibody-Drug Conjugates in Non-small Cell Lung Cancer.

Drugs·2026
Same author

Characterization and clinical management of adverse events following treatment with repotrectinib: a TRIDENT-1 analysis.

The oncologist·2026
Same author

Metastatic Trajectories in Non-Small Cell Lung Cancer Guide Local and Systemic Therapies.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Buruli ulcer in Africa: between innovation and pragmatism.

Nature reviews. Disease primers·2026
Same journal

Author Correction: Atopic dermatitis.

Nature reviews. Disease primers·2026
関連記事をすべて見る

関連する実験動画

Updated: Sep 10, 2025

Experimental Metastasis Assay
08:28

Experimental Metastasis Assay

Published on: August 24, 2010

20.4K

肺転移

Lodovica Zullo1,2, Dimitris Filippiadis3, Lizza E L Hendriks4

  • 1Cancer Medicine Department, Gustave Roussy, Villejuif, France.

Nature reviews. Disease primers
|August 21, 2025
PubMed
まとめ
この要約は機械生成です。

肺の転移は転移性がんに多く見られ 予後と生活の質を著しく悪化させます 転移前のニッチ形成を理解することは,肺がんの転移を標的とする治療法の開発の鍵です.

さらに関連する動画

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
08:54

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Published on: May 20, 2020

9.2K
Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
07:44

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Published on: March 12, 2018

10.2K

関連する実験動画

Last Updated: Sep 10, 2025

Experimental Metastasis Assay
08:28

Experimental Metastasis Assay

Published on: August 24, 2010

20.4K
Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
08:54

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Published on: May 20, 2020

9.2K
Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
07:44

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Published on: March 12, 2018

10.2K

科学分野:

  • 腫瘍学
  • 癌の転移に関する研究
  • 肺医学

背景:

  • 肺転移は転移したがん患者の50%までに影響し,予後が悪い.
  • これらの転移は呼吸不全や痛みなどの症状によって 患者の生活の質を害します
  • 肺転移の発生には複雑な腫瘍分泌因子と微小環境の変化が伴う.

研究 の 目的:

  • 肺転移形成のメカニズムを見直す
  • 肺転移の診断方法について
  • 現在の治療戦略と将来の治療方向性を強調する.

主な方法:

  • 肺転移を引き起こすメカニズムの文献レビュー.
  • 画像と組織学を含む診断方法の分析
  • 肺転移の現在のおよび潜在的な治療法に関する情報の統合.

主要な成果:

  • 腫瘍因子 (VEGF,TGFβ,CCL2),エクソソーム,および微粒子は肺における転移前ニッチを促進する.
  • 診断はイメージングに依存し,原発性肺がんと区別するためにヒストロジーは時々必要です.
  • 治療の決定は,転移の特徴と患者の状態を考慮し,しばしば全身療法を含む.

結論:

  • 転移前ニッチ形成の理解は,新しい予防と治療戦略の開発に不可欠です.
  • 肺転移の標的治療は,まだ満たされていない臨床的需要です.
  • 転移の段階に関する将来的な研究により,適応した治療法が得られるかもしれません.