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Updated: Sep 10, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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マルチソースの疾患類似性ネットワークを通じて,コンピュータによる薬物再定位の改善

Duc-Hau Le1

  • 1School of Information and Communications Technology, Hanoi University of Science and Technology, No. 1 Dai Co Viet, Hai Ba Trung, Hanoi, Vietnam. hauld@soict.hust.edu.vn.

Scientific reports
|August 21, 2025
PubMed
まとめ

この研究では,統合された疾患ネットワークを用いた新しい計算による薬物再定位法が導入され,新しい薬物と疾患の関連性の予測を大幅に改善しました. このアプローチは既存の方法を上回り,臨床的に重要な薬物疾患の関連性を特定します.

キーワード:
病気のマルチプレックスネットワーク薬物の位置変更マルチソース疾患類似ネットワークマルチプレックス・ヘテロジェネスネットワークランダムウォークと再起動 (RWR)

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