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Updated: Sep 10, 2025

Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
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Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease

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アルドース・リダクタゼに対するエパルレスタットおよびラニルレスタットのような化合物の構造による識別と評価: 糖尿病神経疾患の治療管理

Mohd Shahnawaz Khan1, Dharmendra Kumar Yadav2, Moyad Shahwan3,4

  • 1Department of Biochemistry, College of Science, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.

ChemistryOpen
|August 22, 2025
PubMed
まとめ

アルドース還元酵素 (ALDR) を標的とする新しい阻害剤が,糖尿病の合併症のために特定されました. CID 45110135とCID 5864377という2つの有望な薬剤候補は,糖尿病神経病の新たな治療法の開発の可能性を示しています.

キーワード:
アルドース還元酵素阻害剤結合親和性糖尿病性神経症分子ダイナミクスシミュレーション仮想スクリーニング

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