腎臓の質量が減少した転移性腎臓細胞がん患者における急性腎臓損傷に対する経皮腎臓生検の安全性
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PubMedで要約を見る
まとめ
この要約は機械生成です。経皮腎臓生検は,転移性腎臓細胞癌 (mRCC) や急性腎臓損傷 (AKI) の患者に安全である. この研究では,PRBは腎臓の質量低下のmRCC患者で管理可能な合併症に関する貴重な診断情報を提供した.
科学分野
- 腎臓科
- 腫瘍学
- 介入放射線学
背景
- 経皮腎生検 (PRB) は,全身がん治療 (SACT) を受けている転移性腎細胞癌 (mRCC) 患者の急性腎損傷 (AKI) の診断に不可欠です.
- RCCの発生率の増加とSACTの使用は,PRBを必要とする腎臓質量減少または単一腎臓 (SK) を有するmRCC患者の増加につながります.
- SKにおけるPRBの安全性に関するデータは限られており,透析を必要とする合併症に関する懸念が高まっている.
研究 の 目的
- SACT中にAKIを発症したmRCC患者におけるPRBの安全性とアウトカムを評価する.
- 他の転移性固体悪性腫瘍とSACT中のAKI患者におけるPRBの安全性を評価する.
主な方法
- SACT中に腎臓の質量およびAKIが減少した12人のmRCC患者における13人のPRBの遡及症例シリーズ.
- SACT中に転移した固体悪性腫瘍とAKIを患った6人の患者で6つのPRBを含む.
- 副作用は記録され,管理され,合併症の評価を図示した.
主要な成果
- 大半のPRB (mRCCでは11例,転移性固体悪性腫瘍では5例) は無事であった.
- 合併症には1件の大出血 (AVフィスチュラ) と1件のマクロヘマチュリアがmRCC患者で発生した.
- 転移した固体悪性腫瘍の1人の患者は小さな周周周血腫を発症した.
結論
- 合併症は慎重に管理する必要がありますが,PRBはSACT中に腎臓質量およびAKIが減少したmRCC患者にとって安全であるようです.
- これらの特定の患者グループでは,PRB後のより長い観察期間が推奨されます.
- 腎臓の質量が減少したmRCC患者におけるPRBのコンセンサスガイドラインを確立するためにさらなる研究が必要である.
関連する概念動画
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