経口用ニアシンと局所用ニトログリセリンは,顔置換手術後のニコチン関連の合併症を予防する
PubMedで要約を見る
まとめ
この要約は機械生成です。口服用ニアシンと局所用ニトログリセリンは フェイスリフト手術後の皮膚フラップの合併症を 効果的に予防します この治療は,ニコチン使用者のフラップ・イシュケミアを軽減し,既存のイシュケミアを有する患者のアウトカムを改善しました.
科学分野
- 整形 術
- 皮膚科
- 薬理学について
背景
- ニコチンの使用は フェイスリフト手術後の皮膚フラップの合併症の 重要な危険因子です
- 血性フラップは 傷の治癒が悪くなり 美学的な変形を引き起こします
研究 の 目的
- ニコチン関連の皮膚フラップの合併症を減らすために,経口用ニアシンと局所用ニトログリセリンの有効性を評価する.
- 既存のフラップ・イシェミアの治療効果を評価する.
主な方法
- 18ヶ月間にわたる40人のフェイシャルリフト患者の遡及観察研究.
- 患者にはニコチン使用者と非ニコチン使用者が含まれており,フラップ・イシュケミアの兆候がありました.
- 治療には,経口用ニアシンと局所用ニトログリセリンの予防的または治療的使用が含まれていました.
主要な成果
- 治療を受けた22人のニコチン使用者において,フラップ・イシュケミアは発生しなかった.
- 4人の喫煙者が初期発血で3~5日以内に回復し,1人は回復が遅れた.
- 非ニコチン使用者の3〜7日間で,不血症によるフラップの改善が見られた.
結論
- 経口用ニアシンと局所用ニトログリセリンは,特にニコチン使用者における皮膚フラップ・イシュケミアの予防に安全で有効です.
- 併用療法では,既存の不血症のフラップを長期にわたる合併症なしで成功裏に治療しました.
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