関連する実験動画

Updated: Sep 10, 2025

2D and 3D Matrices to Study Linear Invadosome Formation and Activity
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Published on: June 2, 2017

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細胞成熟の"形変体"としてのインバドソーム:メガカリオサイトからの洞察

Frédérique Gaits-Iacovoni1

  • 1Unité de Biologie Moléculaire, Cellulaire et du Développement (MCD, UMR 5077), Centre de Biologie Intégrative (CBI, FR 3743), Université de Toulouse, CNRS, UPS, Toulouse, France.

Frontiers in cell and developmental biology
|August 22, 2025
PubMed
まとめ

インバドソームとポドソームは,細胞とECMの相互作用のためのアクチン構造です. メガカリオシトの線形ポドソームは 機械的な牽引によって細胞外マトリックスを再構成し,腫瘍の侵入を超えた役割を明らかにする.

キーワード:
CDC42 GTPアゼについてコラーゲン I細胞骨格細胞外マトリックス線形インバドソームメガカリオサイトメタロプロテインゼポドソーム

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