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Updated: Sep 10, 2025

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice
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Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice

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腸内微生物が微生物群-腸-脳軸を通してうつ病に及ぼす影響のメカニズム

Xiangyan Zhou1,2, Sixing Wang1,3, Xiaohui Wang4

  • 1Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Frontiers in nutrition
|August 22, 2025
PubMed
まとめ

腸内微生物群は,SCFAの代謝や免疫相互作用などのメカニズムを通じて,腸内微生物群-脳軸を通してうつ病に影響を与えます. 微生物群を標的とした治療は うつ病の治療の可能性を示しています

キーワード:
MGB軸うつ病腸内微生物群メタボリズム神経炎症神経伝達物質

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