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Updated: Sep 10, 2025

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down
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乳糖化:腫瘍の微小環境における薬剤耐性の新たな要因

Chunwei Li1,2,3, Ziqiang Liu2,3, Dezheng Kong2

  • 1National Engineering Laboratory for Internet Medical Systems and Applications, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.

Cancer drug resistance (Alhambra, Calif.)
|August 22, 2025
PubMed
まとめ

ラクチレーションは翻訳後の改変であり,遺伝子発現とDNA修復を変化させることで腫瘍の薬剤耐性を引き起こす. ラクチレーションをターゲットにすることで 癌の治療抵抗性を克服する見込みのある戦略が生まれます

キーワード:
ラクティレーション薬剤耐性エピジェネティック腫瘍の微小環境

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