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Updated: Sep 10, 2025

Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans
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治療に抵抗する統合失調症患者におけるクロザピンの投与量減少:症例シリーズ

Mohammed A Alarabi1,2, Akash Prasanna Kumar1, Valerie Powell1

  • 1Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), 1051 Queen Street West, Toronto, Ontario M6J 1H3, Canada.

Schizophrenia bulletin
|August 22, 2025
PubMed
まとめ

治療抵抗性統合失調症 (TRS) の患者におけるクロザピンの投与量を減らすと,再発のリスクが高くなります. クロザピンの濃度に従って徐々に投与量を減らすことで,このリスクを軽減することができるが,より大規模な研究が必要である.

キーワード:
抗精神病薬描写する精神障害再発防止寛解

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