急性血性脳卒中後の感染率と関連因子:単一センターでの5年間の遡及研究
Weny Rinawati1,2, Aryati Aryati3,4, Abdulloh Machin4,5,6
1Doctoral Program in Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.
Epidemiologia (Basel, Switzerland)
|August 22, 2025
まとめ
急性不全性脳卒中 (AIS) に続く感染症は一般的であり,主にK. pneumoniaeのような細菌によって引き起こされます. COVID-19 パンデミックは感染パターンと抗菌剤耐性を変化させ,早めの食欲不全検査などの予防措置の必要性を強調しました.
科学分野:
- 神経学
- 感染症
- 微生物学
背景:
- 脳卒中の後の感染は 患者の状態を著しく悪化させますが アジアの人口に関するデータは まだ不足しています
- 脳卒中後の感染症の 微生物の状況を理解することは 標的型治療に不可欠です
研究 の 目的:
- 急性不全性脳卒中 (AIS) の後に感染を引き起こす病原体の細菌と真菌のプロファイルを決定する.
- COVID-19 パンデミックにおける感染率と関連因子の変化を分析する.
主な方法:
- 2018年から2022年の間に入院した599人のAIS患者 (≥18歳) の遡及研究.
- 微生物培養は感染確認の黄金基準として使用されます.
- 多重ロジスティック回帰で 感染に関連する要因を分析した.
主要な成果:
- 孤立した病原体による感染の発生率は21. 4%で,主にによる感染でした.
- 一般的な細菌の病原体には,K. pneumoniae,E. coli,A. baumannii,S. aureusが含まれ,真菌感染症はまれでした.
- COVID-19の間,抗菌剤耐性が増加しました. 集中治療室と脳卒中治療室では 感染のリスクが減りました 尿管はリスクを増やした (非COVID),ステロイド,TPN,気管切除は保護的であった (COVID).
結論:
- AIS後の感染率とリスク要因は,COVID-19時代に進化した.
- ディスファギーの早期スクリーニングを含む予防戦略は,感染リスクを軽減するために不可欠です.
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