ルーマニアのムレシュ郡で実施された,高血圧患者における血圧の遵守,持続性,および血圧制御に関する横断的な研究

Radu Tatar¹, Marius-Stefan Marusteri², Dragos-Gabriel Iancu^1,2

¹Doctoral School, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania.

Medical sciences (Basel, Switzerland)

|August 22, 2025

まとめ

抗高血圧療法への不服従は一般的であり,男性の性別と若い年齢は不服従を予測する. 血圧をコントロールし心血管疾患のリスクを減らすには薬の利用可能性と継続性を確保することが重要です

科学分野:

心血管医学
主要なケア
薬学経済学

背景:

抗高血圧療法への不従順は,世界中で治療を受けた患者のほぼ半分に影響を与え,血圧の制御不能と心血管疾患の増加につながります.
抗高血圧治療の持続率は,しばしば最初の1年以内に60%を下回るため,初等医療環境における遵守および持続性の評価が必要である.

研究の目的:

ルーマニアのムレシュ郡のプライマリケア患者の抗高血圧療法への従順性と持続性を評価する.
対象となる介入を促すための,変更可能なリスク要因を特定する.

主な方法:

ルーマニアのムレス郡で1年間治療を受けた399人の高血圧成人 (≥18歳) を対象とした横断的な研究.
ルーマニアで検証されたHill- Bone Compliance to High Blood Pressure Therapy Scale (HBCTS) を使用して評価され,平均動脈圧 (MAP) < 100 mmHgで確認されました.
多変量ロジスティック回帰とROC曲線解析により,アデレンス予測要因が特定され,アデレンス持続性は360日間の医療従事者への関与指標で評価された.

主要な成果:

効果的な血圧制御 (MAP < 100 mmHg) は,参加者の45. 9%で達成されました.
男性の性別 (OR = 0. 47) と年少の年齢 (OR = 1. 04 年間) は,独立して不適格性を予測した.
治療期間は血圧のコントロールと強く相関する (r = - 0. 50); 67. 7%の患者で血圧のコントロールが改善された.

結論:

検証されたHBCTS (≥51ポイント) は,ルーマニアのプライマリケアにおける効率的なスクリーニングツールです.
治療対象日数は血圧制御の最も強力な予測指標であり,薬剤の可用性を強調しています.
男性や若い患者を対象とした介入は薬剤の継続性モニタリングと併せて心血管疾患の罹患率を減らすことができます

キーワード:

高血圧治療スケール (HBCTS) に適合するロシア高血圧薬の順守主要なケア

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