SARS-CoV-2 主要プロテアゼは肝臓のインスリンシグナル伝達とグルコース摂取を調節する:COVID-19後の糖尿病発生への影響

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Updated: Sep 10, 2025

An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes
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Praise Tatenda Nhau1, Mlindeli Gamede2, Andile Khathi3

  • 1Pharmacology Division, Faculty of Pharmacy, Rhodes University, Makhanda 6139, South Africa.

Pathophysiology : the official journal of the International Society for Pathophysiology
|August 22, 2025
PubMed
まとめ

SARS-CoV-2 メインプロテアゼ (Mpro) は肝臓細胞のグルコース吸収とインスリンシグナル伝達を損なう. このウイルスのプロテアゼは代謝機能障害と炎症に寄与し,潜在的なウイルス後合併症を強調する.

キーワード:
Mpro についてSARS-COV-2について糖尿病 糖尿病インスリンインスリン抵抗性肝臓

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