口腔健康状態とX関連低リンパ性症の子供の親の意識:症例対照研究
Victoria Zlateva1, Krasimir Hristov1, Zdravka Todorova2
1Department of Pediatric Dentistry, Faculty of Dental Medicine, Medical University of Sofia, 1000 Sofia, Bulgaria.
Reports (MDPI)
|August 22, 2025
まとめ
X関連低リン酸性血症 (XLH) の子供は,健康な子供と比較して,口腔衛生が著しく低下し,空洞や誤閉症の割合が高くなります. 歯科リスクに対する親の認識は極めて低いため 改善された管理戦略が必要である.
科学分野:
- 遺伝 と 代謝 障害
- 小児歯科
- 公衆衛生
背景:
- X関連低リン酸性血症 (XLH) は,リン酸代謝と骨の鉱化に影響する珍しい遺伝疾患である.
- XLHと歯科合併症の関連性は十分に確立されていません.
- 特にブルガリアでは,XLH患者における口腔の健康状態と歯科リスクに対する親の認識に関するデータが限られている.
研究 の 目的:
- ブルガリアのXLH児の歯の状態 (口腔衛生,下痢,不良) を評価する.
- XLHにおける潜在的な歯科合併症に対する親の認識を評価する.
- XLH児の口腔健康を,年齢と性別を合わせた健康な対照群と比較する.
主な方法:
- 11人のXLH患者 (平均年齢2. 5~17歳) と11人の健康な対照群を比較した横断研究.
- 口腔衛生指数,虫歯の有病率,悪口の評価による歯の状態の評価
- 親の意識はアンケートで評価された.
- XLH患者には,ブルースマブ治療を受けている,または待機中の患者も含まれていた.
主要な成果:
- XLH患者では,対照群に比べて口腔衛生が著しく低下 (p=0. 013) し,虫歯の罹患率が高かった (p=0. 001).
- XLHの子供の66. 67%は口腔衛生が不良で,平均6. 45のカリアス病変があった.
- XLH児の63. 64%に悪口があり,自発的な内歯感染症は18. 18%に発生しました.
結論:
- XLHの子どもは口腔衛生が悪く,虫歯の負担が高く,不適切な閉塞が頻繁に起こる.
- XLHに関連する歯科リスクに関する親の認識は不足しています.
- XLH患者の口腔健康管理には,日常的な評価と親教育を含む統合された歯科ケアが不可欠です.
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