関連する実験動画

Updated: Sep 10, 2025

Comparative Lesions Analysis Through a Targeted Sequencing Approach
08:16

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Published on: November 5, 2019

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JAK/STATの謎は,変異異異質性,免疫欠陥,そして標的治療の出現

Durmus Burak Demirkaya1,2,3, Burkay Cagan Colak1,2,3, Asena Pinar Sefer4

  • 1Division of Pediatric Allergy and Immunology, Faculty of Medicine, Marmara University, Istanbul, Türkiye.

Expert review of clinical immunology
|August 22, 2025
PubMed
まとめ

ジャヌスキナーゼ/シグナルトランスデューサーおよびトランスクリプションアクティベーター (JAK/STAT) 経路の調節不良は免疫障害を引き起こす. これらのJAK/STAT経路の異常を理解することは,より良い患者の結果のための標的治療の開発の鍵です.

キーワード:
JAK阻害剤JAK/STAT についてSTAT1 機能の獲得STAT3の機能増強STAT6 機能の獲得免疫の先天的な誤り

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