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Updated: Sep 10, 2025

Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyltroponeiron
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Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyltroponeiron

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ディボロン媒介サイクライゼーションによる特権ダイヒドロペトリディノンのオン-DNA合成

Xudong Wang1,2, Xuanjing Shen1,2, Yueyue Xia3

  • 1State Key Laboratory of Drug Research, Shanghai Institute of MateriaMedica, Chinese Academy of Sciences, Shanghai 201203, P. R. China.

Organic letters
|August 22, 2025
PubMed
まとめ

新しいディボロン媒介法により,7,8-ディヒドロ-6 (((5H) -ペトリディノン誘導体の効率的なDNA合成が可能である. このブレークスルーは,軽度な,水性コンパティブルな条件を用いた薬剤発見における DNA 暗号化化学ライブラリ (DECL) の化学空間を拡大します.

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