アピゲニンの栄養補充は,死腸炎を患っている brojler の腸内損傷を和らげる
Yiming Li1, Qiyuan Zhao1, Qi Zhang1
1College of Animal Science and Technology, Guangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, Guangxi grass station, Guangxi University, Nanning, 530004, Guangxi, China.
Poultry science
|August 22, 2025
まとめ
食用アピゲニンサプリメントは,死腸炎 (NE) に悩んだ brojler の成長と腸の健康を改善しました. アピゲニンは抗酸化作用を強め,免疫反応を調節し,NEによる腸損傷を効果的に軽減しました.
科学分野:
- 鶏肉科学
- 動物の栄養
- 免疫学
背景:
- 死腸炎 (NE) はブローカーの重要な病気で,かなりの経済的損失をもたらします.
- NEは成長能力,腸壁の整体性,免疫機能に悪影響を及ぼします.
- 食生活への介入は NEの管理とブローカーの健康改善に不可欠です.
研究 の 目的:
- 食中のアピゲニンの成長能力,腸内障壁の整合性,およびNEのブローラーにおける免疫反応の影響を調査する.
- NEによる病理的変化を緩和するアピゲニンの可能性を評価する.
- 鶏肉の健康のために最適なアピゲニン補給量を決定する.
主な方法:
- 合計144匹の brojlerは6つのグループに分けられ,NEはEimeria maximaとClostridium perfringensによって誘発された.
- アピゲニン (500 mg/ kg) を化後の24日から28日間で摂取した.
- 成長性能,腸の形態,抗酸化能力,免疫サイトカインのレベルを評価した.
主要な成果:
- NEは,平均日益率 (ADG) と飼料変換比率 (FCR) を著しく低下させた.
- NEは抗酸化能力の低下,腸内浸透性の増加,および変異したサイトカインプロファイル (IL- 1β,IL- 6,TNF- α,IL- 10)
- アピゲニン補給 (500 mg/ kg) は,ADGとFCRを効果的に改善し,抗酸化活性を増強し,腸の形態を回復し,免疫応答を調節しました.
結論:
- 食用アピゲニンの補充は,ニワトリのNE誘発の悪影響を軽減する有望な戦略です.
- アピゲニンは抗酸化能力を高め,免疫反応を調節し,それによって腸のバリア機能を改善します.
- 他の家禽の病気におけるアピゲニンの役割と最適な用量については,さらに研究が進められます.
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