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粘着性のあるビジネス:分子接着剤によるCRBNの亜鉛指標的の合理化

Jonathan W Bushman1, Patrick Ryan Potts1

  • 1Induced Proximity Platform, Amgen Research, Thousand Oaks, CA, USA.

Molecular cell
|August 22, 2025
PubMed
まとめ

研究者はCRBNを標的にする分子接着剤によって分解できる 亜鉛指を持つヒトのタンパク質を特定しました この研究は 難しいタンパク質を標的とする 規則を洗練し 治療の選択肢を広げています

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