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Updated: Sep 10, 2025

Author Spotlight: Elucidating the Pathways of TFH Cell Differentiation in Acute LCMV Challenges
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転写因子 BACH2 は,HIV-1 の持続性を促進するために組織内定の記憶T細胞プログラムを形成する

Yulong Wei1, Haocong Katherine Ma1, Michelle E Wong1

  • 1Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06519, USA.

Immunity
|August 22, 2025
PubMed
まとめ

ヒト免疫不全ウイルス1型 (HIV-1) は,長寿命の組織内記憶T細胞 (Trms) の内に存在します. 転写因子BACH2は,これらの腸内TRMを形作り,HIV-1の持続性を影響する.

キーワード:
BACH2 についてHIV 治療法HIV-1 貯蔵庫HIV-1特異性CD8 ((+) T細胞T細胞のクローン拡張T細胞ホメオスタシス腸に粘膜免疫単細胞マルチオミック組織内定の記憶T細胞

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