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Updated: Sep 10, 2025

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target

Published on: May 10, 2022

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B型肝炎ウイルスのカプシドアセンブリモデュレータのコンピューティング開発における進歩

Ke Liu1, Shaoqing Du2, Weiqiao Deng3

  • 1School of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong 276000, China; School of Chemistry and Chemical Engineering, Shandong University, Qingdao, Shandong 266237, China.

Drug discovery today
|August 22, 2025
PubMed
まとめ

B型肝炎ウイルス (HBV) のカプシドアセンブリモジュール (CAM) は,ウイルスの複製を抑制する鍵です. 機能的なHBV治療のための効果的なCAMを開発するためのコンピュータ支援薬剤設計戦略が強調されています.

キーワード:
カプシド・アセンブリ・モジュールカプシドタンパク質コンピューター・アシスタント・ドラッグ・デザインB型肝炎ウイルス

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関連する概念動画

Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
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