編集: 産前抗精神病薬の暴露による神経発達の結果
1Riverside University Health System, Riverside, California.
まとめ
妊娠中の抗精神病薬の使用は増加しているが,高品質の安全性に関する証拠は限られている. 医師は妊婦の治療決定を導くためにより多くのデータが必要です.
科学分野:
- 生後期の精神科
- 妊娠中の薬用警戒
- 生殖毒学
背景:
- 妊婦の抗精神病薬の使用は2001年から2010年の間に大幅に増加しました.
- この期間中,メディケイド保険の妊婦150万人以上が非典型的な抗精神病薬を処方されました.
- 主な診断は双極性障害で,クエチアピンとアリピプラゾルが最も多く投与された薬です.
研究 の 目的:
- 妊婦の抗精神病薬の使用が 増加していることに注目します
- 妊娠中にこれらの薬の安全性に関するさらなる研究が必要であることを強調します.
- 現在の処方パターンと関連する診断の傾向について医療提供者に知らせる.
主な方法:
- メディケイド保険の妊婦の大群からの処方データ分析
- 2001年から2010年までの薬剤の配給傾向の調査
- 主要な診断と最も頻繁に投与される抗精神病薬の特定
主要な成果:
- メディケイドの妊娠中の女性150万人以上が 2001年から2010年にかけて 非典型的な抗精神病薬の処方箋を記入しました
- 抗精神病薬の使用率は0. 4%から1. 3%に増加した.
- 主な診断は双極性障害で,クエチアピンとアリピプラゾルが最も多く投与された薬です.
結論:
- 妊娠中の抗精神病薬の使用の増加は,緊急の臨床的注意とさらなる安全性研究を必要とします.
- 双極性障害は,妊婦の抗精神病薬の使用の重要な指標です.
- クエチアピンとアリピプラゾールは,産後精神科のケアにおいて顕著であり,特定の安全性評価を正当化しています.
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