BRAF/ MEK 阻害剤療法中に抵抗性心房細動を伴うフルミナント心筋炎
Andrea Lalario1, Filippo Maria Rubbo1, Giulia Bassetto1
1Center for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department, European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart-ERN GUARD-Heart, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, Trieste, Italy.
JACC. Case reports
|August 22, 2025
まとめ
メラノーマに対するBRAF/ MEK阻害剤治療は,まれだが致命的な心筋炎を引き起こす. この症例は,症状のない患者でも,この重度の有害事象を早期に検出するために,心臓のモニタリングの必要性を強調しています.
科学分野:
- 腫瘍学
- 心臓病科
- 薬理学について
背景:
- BRAF/MEK阻害剤治療は メラノーマの重要な治療法であり,生存率を改善します.
- 心筋炎は,この治療の希少な,しかし深刻な潜在的な合併症です.
- 患者の管理には心筋炎の早期発見が不可欠です.
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