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Updated: Sep 10, 2025

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
11:34

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Published on: May 5, 2014

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シリコスクリーニングおよび実験的検証では,リボフラビンは,SARS-CoV-2に対するRNA標的抗ウイルス剤として識別される

Chae-Hong Jeong1, Yoo Jin Na1, Tae Yong Kim1

  • 1Division of Clinical Research, Center for Emerging Virus Research, National Institute of Infectious Diseases, Korea National Institute of Health, 212 Osongsaengmyeong2-ro, Osong-eup, Heungdeok-gu, Cheongju, 28160, Republic of Korea.

Scientific reports
|August 22, 2025
PubMed
まとめ

この研究は,リボフラビンをSARS-CoV-2に対するRNA標的抗ウイルス剤として再利用した. リボフラビンは,ワクチン接種中に投与されたとき,ウイルスの複製を抑制することによって,選択的な抗ウイルス活性を示した.

キーワード:
抗レトロウイルス薬物の再利用シリコンRNA二次構造リボフラビンSARS-CoV-2について

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