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Updated: Sep 10, 2025

Excitotoxic Stimulation of Brain Microslices as an In vitro Model of Stroke
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カイナート受容体GluK2-Neto2複合体の活性化

Shanti Pal Gangwar1, Maria V Yelshanskaya1, Laura Y Yen1,2

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Nature structural & molecular biology
|August 22, 2025
PubMed
まとめ

構造は,カイナート受容体 (KAR) の活性化と,Neto2補助サブユニットの機能を調節する方法を示しています. Neto2結合は受容体のゲートダイナミクスを変化させ,興奮神経伝達と潜在的な治療目標に影響を与えます.

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