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RAS結合ペプチドを用いて選択的にmTORC2を抑制するためにRAS- mSIN1の相互作用を活用する:乳癌の転移への影響

  • 0CSIR-Central Drug Research Institute (CDRI), Lucknow, Uttar Pradesh, India.
Oncogene +

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2025年8月23日

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The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
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